Tag: Folate deficiency
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Frameworks for Internal Medicine (2018)
Frameworks for Internal Medicine (2018) is a very popular 768-page book which lays out a fairly detailed algorithmic approach to internal medicine. It is a single author book, which is a very rare accomplishment for an author of a book of this size and scope. The book employs mainly two teaching methods: the algorithmic approach…
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Macrocytic Anemia: The Workup
The workup for macrocytic anemia should include some or all the following: Peripheral blood smear Hypersegmented neutrophils and macroovalocytes → B12 or folate deficiency. Pancytopenia → advanced B12 deficiency Target cells → chronic liver disease (anemia and thrombocytopenia are also seen). Pseudo-Pelger-Huët cells → myelodysplastic syndrome. For vitamin B12 deficiency Vitamin B12 levels Methylmalonic acid and…