Tag: Bleeding disorders
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Disseminated Intravascular Coagulation (DIC)
Introduction Disseminated Intravascular Coagulation (DIC) is a very serious and life-threatining coagulation cascade disorder that is sometimes seen in patients with severe physiologic stressors such as sepsis, obstetric complications (for example, placental abruption, retained products of conception, or amniotic fluid embolization) or major tissue injury from trauma, burns, shock, snake bites, or malignancy (for example, acute promyelocytic leukemia).…
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Hematologic Emergencies
White cell disorders Tumor lysis syndrome → allopurinol, hemodialysis Leukostasis (leukemia patient with very high white cell count and neurological changes) → leukophoresis Acute hyperviscosity syndrome (in Waldenström macroglobulinemia) → plasmapheresis Red blood cell disorders Methemoglobinemia → oxygen, methylene blue Sickle cell emergencies: Acute calculous cholecystitis → antibiotics, consider surgical intervention Acute splenic sequestration crisis (shock, LUQ pain, acute…