Tag: Angioedema without urticaria

The differential diagnosis for angioedema without urticaria (“hives”) is fairly narrow, and requires a unique workup and management strategy. Clinical presentation Patients present with sudden, profound, non-erythematous, non-pruritic localized edema of distensible tissues such as lips, eyelids, tongue and external genitalia. The key here is that they are negative for hives, itching, or bronchospasms. Two…